MediaElement is an audio an video player which is written in pure HTML5 and CSS. Older browsers are supported by Custom Flash and Silverlight players that mimic the HTML5 MediaElement API.
Media Element is skinnable, and offers plugins for popular platforms such as WordPress, Drupal, Joomla, etc.
→ Visit http://mediaelementjs.com/
Scott Andrew’s HTML5 audio player
This player is very minimalist but works well. Great to use when you do not need playlists or any fancy effects!
Here is a great player, probably my favorite from the whole list. Speakker is super easy to set up and comes out of the box in two variations and with incredible options of customization: Flexible dimensions, unlimited colors, etc…
Speakker is cross-browser compatible and have a Flash fallback for old browsers.
and two different button sets for light and dark themes.
→ Visit http://www.speakker.com/
MooTools HTML5 Audio Player
Universal HTML5 Audio Player
This player is the only one from the list which isn’t free. But it’s cheap ($5 only!) and works well. It have lots of useful features, such as a way to protect your audio from being hijacked by using a beep overlay, which is a great solution for commercial uses.
Want to see what you can do with Sound Manager 2? Then visit http://wheelsofsteel.net/ for an awesome demo!
jplayer is a jQuery plugin which have been my audio player of choice for several months because of its simplicity. A great tool which can also play videos.
→ Visit http://jplayer.org/
<audio> tag to be used anywhere. It uses native
<audio> where available and an invisible flash player to emulate
<audio> for other browsers. It provides a consistent html player UI to all browsers which can be styled used standard css.
HTML5 Audio Player Bookmarklet
This bookmarklet adds an audio player to play linked audio files on any page. It can be used on any page which has links to downloadable audio files. A great tool to stream audio instead of downloading!